Analysis of the decompressive treatment of the vertebral canal through the trans-spinal approach / Análise do tratamento descompressivo do canal vertebral pela via transespinhosa / Análisis del tratamiento descompresivo del canal vertebral mediante el enfoque transespinal

ABSTRACT Objective: The spinous process separation technique is a less invasive surgical technique for treating lumbar canal stenosis. The objective is to evaluate this technique's results in treating lumbar canal stenosis. Method: Thirty patients with lumbar spinal canal stenosis underwent surgical treatment using the spinous process separation technique and were evaluated in the 3-year postoperative period using the Denis Pain and Work Scale and by the SF-36 questionnaire and radiographic evaluation of the operated segment. Results: In the evaluation of the Denis pain scale, 21 (70%) patients had no pain (P1), and nine (30%) patients reported minimal low back pain, not needing medication (P2). Denis' work schedule showed that nine (30%) patients had restrictions on returning to their previous work activity (W2), and 21 (70%) patients were classified as W1. The SF-36 questionnaire showed results of 81.25 for physical aspects (PA), 81.9 for functional capacity (FC), 81.3 for emotional aspects (EA), 64.3 for vitality (V), 65.9 for mental health (MH), 81.98 for social aspects (SA), 75.6 for pain (P) and 68.1 for general health status (GHS). In addition, there were no radiographic signs of instability of the operated vertebral segment in the radiographic evaluation. Conclusion: The decompression of the lumbar spinal canal using the spinous process separation technique showed good results in the evaluated patients three years after the operation. Level of Evidence II, Retrospective Comparative Study.

Resumo: Objetivo: A técnica de separação do processo espinhoso é uma técnica cirúrgica menos invasiva para o tratamento da estenose do canal lombar. O objetivo é avaliar os resultados dessa técnica no tratamento da estenose do canal lombar. Método: Trinta pacientes portadores de estenose do canal vertebral lombar foram submetidos ao tratamento cirúrgico por meio da técnica da separação do processo espinhoso, tendo sido avaliados no período de três anos de pós-operatório, por meio da escala de dor e de trabalho de Denis, pelo questionário SF-36 e avaliação radiográfica do segmento operado. Resultados: Na avaliação da escala de dor de Denis, 21 (70%) pacientes não apresentavam dor (P1) e nove (30%) pacientes relataram dor mínima lombar, não necessitando medicação (P2). A escala de trabalho de Denis evidenciou que nove (30%) pacientes apresentavam restrições ao retorno à atividade prévia de trabalho (W2) e 21 (70%) pacientes foram classificados como W1. O questionário SF-36 apresentou resultados 81,25 para aspectos físicos (AF), 81,9 para capacidade funcional (CF), 81,3 para aspectos emocionais (AE), 64,3 para vitalidade(V), 65,9 para saúde mental (SM), 81,98 para aspectos sociais (AS), 75,6 para dor (D) e 68,1 para estado geral de saúde (EGS). Não foram observados sinais radiográficos de instabilidade do segmento vertebral operado na avaliação radiográfica. Conclusão: A descompressão do canal vertebral lombar por meio da técnica de separação do processo espinhoso apresentou bons resultados na avaliação num período de três anos de pós-operatório dos pacientes avaliados. Nível de Evidência II, Estudo Retrospectivo Comparativo.

Resumen: Objetivo: La técnica de separación de la apófisis espinosa es una técnica quirúrgica menos invasiva para el tratamiento de la estenosis del canal lumbar. El objetivo es evaluar los resultados de esta técnica en el tratamiento de la estenosis del canal lumbar. Método: Treinta pacientes con estenosis del conducto raquídeo lumbar fueron intervenidos quirúrgicamente mediante la técnica de separación de la apófisis espinosa, y fueron evaluados en el postoperatorio de tres años mediante la Escala de Dolor y Trabajo de Denis, mediante el cuestionario SF-36 y evaluación radiográfica del segmento operado. Resultados: En la evaluación de la escala de dolor de Denis, 21 (70%) pacientes no presentaron dolor (P1) y nueve (30%) pacientes refirieron dolor lumbar mínimo, sin necesidad de medicación (P2). La escala de trabajo de Denis mostró que nueve (30%) pacientes tenían restricciones para regresar a su actividad laboral anterior (W2) y 21 (70%) pacientes fueron clasificados como W1. El cuestionario SF-36 arrojó resultados 81,25 para aspectos físicos (AF), 81,9 para capacidad funcional (CF), 81,3 para aspectos emocionales (AE), 64,3 para vitalidad (V), 65,9 para salud mental (SM), 81,98 para aspectos sociales (AS), 75,6 para dolor (D) y 68,1 para estado general de salud (EGS). No hubo signos radiográficos de inestabilidad del segmento vertebral intervenido en la evaluación radiográfica. Conclusión: La descompresión del canal espinal lumbar mediante la técnica de separación de apófisis espinosa mostró buenos resultados en la evaluación de un período de 3 años después de la operación de los pacientes evaluados.

Minimally invasive laminar lift and posterior cervical laminoplasty via the intermuscular approach: a canine model study

Purpose: This study aimed to develop a minimally invasive surgical procedure for laminar lift and posterior cervical laminoplasty via the intermuscular approach using a canine model. Methods: Six Alaskan dogs were used for developing the surgical approach. The bilateral laminae of C3-7 were cut with an ultrasonic osteotome and fixed with bilateral plates to maintain the lamina lifting and reshape a wider spinal canal. The important structures, such as ligaments, supraspinous ligaments, interspinous ligaments, and ligamentum flavum were preserved. The therapeutic effect was evaluated by preoperative and postoperative imaging results and neck mobility. Results: The surgical procedures were all successfully performed in the 6 animals. All the dogs survived well within 1 year of postoperative follow-up. The postoperative neck mobility was as good as the preoperative one. Computed tomography results showed that the anteroposterior diameter of the spinal canal was successfully enlarged and maintained well. Conclusions: The minimally invasive surgical procedure for laminar lift and posterior cervical laminoplasty via the intermuscular approach was feasible in a canine model, which might be applied in clinical practice.

Impact of the covid-19 pandemic on the surgical treatment of spine pathologies in sus / Impacto da pandemia da covid-19 no tratamento cirúrgico de patologias de coluna no sus / Impacto de la pandemia de covid-19 en el tratamiento quirúrgico de patologías de la columnavertebral enel sus

ABSTRACT Objective: To evaluate the impact of the COVID-19 pandemic on spine surgeries performed by SUS. To identify changes in surgical volume, as well as which procedures and regions of Brazil were most affected. To correlate such changes with literature data. Methods: A retrospective, descriptive study was conductedwith an analysis of the databases available to the public on the performance of spinal surgical procedures by SUS during the period from 2017 to 2021. The databases were created from variables of interest available in the SIH (Hospital Information System) of the SUS Information Technology Department website (DATASUS; http://datasus.saude.gov.br). The procedures were grouped according to type of surgery, topography, and access route for the construction of tables and statistical analysis. Results: In the years of the pandemic, a greater drop in surgical volume was observed, with a total of 13,276 procedures in 2020 and 12,158 in 2021, equivalent to -28.51% and -34.53%, respectively, of the average of the previous period. Conclusions: Given the paramount importance of attention to the fight against the pandemic, maintaining the level of assistance for spinal pathologies proved to be a great challenge, especially in relation to elective surgical pathologies that, when delayed too much, can seriously impact the quality of life and outcomes of future treatments. Level of Evidence: IV; Retrospective, descriptive.

RESUMO Objetivo: Avaliar o impacto da pandemia de COVID-19 na realização de cirurgias de coluna no SUS. Identificar mudanças do volume de cirurgias, bem como quais procedimentos e regiões do Brasil foram mais afetados. Correlacionar tais mudanças com dados da literatura. Métodos: Realizou-se um estudo retrospectivo, descritivo, com análise de banco de dados disponíveis para o público sobre a realização de procedimentos cirúrgicos de coluna pelo SUS no período de 2017 a 2021. Os bancos de dados foram criados a partir das variáveis de interesse disponíveis no SIH (Sistema de Informações Hospitalares) do site do Departamento de Informática do SUS (DATASUS; http://datasus.saude.gov.br). Os procedimentos foram agrupados de acordo com tipo de cirurgia, topografia e via de acesso para construção das tabelas e análise estatística. Resultados: Nos anos da pandemia observou-se uma queda maior no volume cirúrgico com um total de 13.276 procedimentos em 2020 e 12.158 em 2021, equivalentes a -28,51% e -34,53% com relação à média do período anterior, respectivamente. Conclusões: Diante da importância primordial da atenção ao combate da pandemia, a manutenção da assistência às patologias de coluna revela-se um grande desafio, principalmente com relação a patologias cirúrgicas eletivas que, quando postergadas em demasia, podem impactar de maneira grave a qualidade de vida e resultados de tratamentos futuros. Nível de EvidênciaIV; Estudo RetrospectivoDescritivo.

RESUMEN Objetivo: Evaluar el impacto de la pandemia de COVID-19 en larealización de cirugías de columna en el SUS. Identificar cambios en el volumen de cirugías, así como qué procedimientos y regiones de Brasil se vieron más afectados. Correlacionar dichos cambios con datos de la literatura. Métodos: Se realizó un estudio retrospectivo, descriptivo, con análisis de bases de datos disponibles públicamente sobre la realización de procedimientos quirúrgicos de columna vertebral por el SUS en el período comprendido entre 2017 y 2021. Las bases de datos fueron creadas a partir de las variables de interés disponibles en el SIH (Sistema de Información Hospitalaria) del sitio web del Departamento de Informática del SUS (DATASUS; http://datasus.saude.gov.br). Los procedimientos fueron agrupados según tipo de cirugía, topografía y vía de acceso para la elaboración de tablas y análisis estadístico. Resultados: En los años de pandemia se observó un mayor descenso en el volumen quirúrgico, con un total de 13.276 procedimientos en 2020 y 12.158 en 2021, equivalentes a -28,51% y -34,53% respecto a la media del periodo anterior, respectivamente. Conclusiones: Dada la trascendental importancia de la atención en el combate a la pandemia, mantener la asistencia a las patologías de la columna resulta un gran desafío, especialmente en lo que respecta a las patologías quirúrgicas electivas que, cuando se demoran demasiado, pueden repercutir gravemente en la calidad de vida y en los resultados de futuros tratamientos. Nivel de evidencia: IV; Estudio Retrospectivo Descriptivo.

Impact of obesity on the clinical outcomes of spinal surgery by transpsoas lateral fusion / Impacto da obesidade sobre os desfechos clínicos da cirurgia da coluna por artrodese lateral via transpsoas / Impacto de la obesidad en los resultados clínicos de la cirugía de columna mediante fusión lateral transpsoas

ABSTRACT Introduction: Obesity is a global phenomenon that affects the quality of life of the population. In addition to being a factor that can lead to cases of degeneration in the spine, it can also influence the clinical outcomes of spine surgeries. However, with the development of minimally invasive techniques, the impact of obesity has become uncertain. Methods: A single-center, non-randomized, comparative, observational study, here clinical and surgical outcomes and postoperative complications were analyzed between obese and non-obese patients undergoing LLIF surgery. Results: There was no difference between surgical times and blood loss between the groups; the number of postoperative complications was similar. Both groups showed significant improvement in clinical parameters, but there was no difference between the amount of improvement between the obese and non-obese groups. Conclusion: The present study demonstrated that LLIF is a safe and effective technique regardless of the patient's degree of obesity. Level of Evidence III; Retrospective study.

RESUMO Introdução: A obesidade é um fenômeno global que possui diversos sobre a qualidade de vida da população. Além de ser um fator que pode levar a casos de degeneração na coluna, como também pode influenciar nos desfechos clínicos das cirurgias de coluna. No entanto, com o desenvolvimento de técnicas minimamente invasivas o impacto da obesidade se tornou incerto. Métodos: Estudo de centro único, não-randomizado, comparativo, observacional, onde foram analisados os desfechos clínicos, cirúrgicos e complicações pós-operatórias entre pacientes obesos e não-obesos submetidos a cirurgia de LLIF. Resultados: Não houve diferença entre os tempos cirúrgicos e perda sanguínea entre os grupos, ademais o número de complicações pós-operatórias foi similar entre os grupos. Ambos os grupos apresentaram melhora significativa dos parâmetros clínicos, porém não houve diferença entre a quantidade de melhora entre os grupos obeso e não-obeso. Conclusão: O presente estudo demonstrou que o LLIF é uma técnica segura e eficaz independentemente do grau de obesidade do paciente. Nível de evidência III; Estudo retrospectivo.

RESUMEN Introducción: La obesidad es un fenómeno mundial que afecta la calidad de vida de la población. Además de ser un factor que puede conducir a casos de degeneración en la columna, también puede influir en los resultados clínicos de las cirugías de columna. Sin embargo, con el desarrollo de técnicas mínimamente invasivas, el impacto de la obesidad se ha vuelto incierto. Métodos: Estudio observacional, comparativo, no aleatorizado, unicéntrico, donde se analizaron los resultados clínicos, quirúrgicos y las complicaciones postoperatorias entre pacientes obesos y no obesos sometidos a cirugía LLIF. Resultados: No hubo diferencia entre los tiempos quirúrgicos y la pérdida de sangre entre los grupos, además, el número de complicaciones postoperatorias fue similar entre los grupos. Ambos grupos mostraron una mejora significativa en los parámetros clínicos, pero no hubo diferencia entre la cantidad de mejora entre los grupos obesos y no obesos. Conclusión: El presente estudio demostró que la LLIF es una técnica segura y eficaz independientemente del grado de obesidad del paciente. Nivel de Evidencia III; Estudio retrospectivo.

Analgesic Effects of Two Types of Spinal Manipulation in Acute Lumbar Radiculopathy Model Rats / 中国结合医学杂志

OBJECTIVE@#To compare the analgesic effects of two types of spinal manipulation (SM) in acute lumbar radiculopathy (ALR) model rats induced by self-transplantation of autologous nucleus pulposus (ANP), and clarify the therapeutic mechanism.@*METHODS@#Totally 108 male Sprague-Dawley rats were randomly divided into 6 groups by a random number table (18 rats in each group), including a blank group with no interference, a sham operation group with a surgery by making a local soft tissue incision on the left side of L5-6 vertebral segment, a model group with ALR of L5 extraforaminal nerve by ANP self-transplantation without other interference, a sham manipulation (SMA) group with simulating physical rotation, as well as a mobilization (MOB) group with simulating low-velocity and variable-amplitude rotation and a manipulation (MAN) group with simulating high-velocity and low-amplitude rotation. The interventions in SMA, MOB, and MAN groups started 1 day after modeling followed by another 5 treatments at days 3, 5, 8, 10 and 12. Rats in the other 3 groups did not receive any special intervention. Behavioral pain tests of 50% mechanical pain withdrawal threshold (50% PWT) and paw withdrawal latency (PWL) were conducted 1 day before operation followed by another 10 tests on days 1-7, 10, 12 and 14. Immunohistochemical expression of nitric oxide synthase (NOS) was investigated on days 5 and 12 after operation.@*RESULTS@#After 3 experimental SM interventions, 50% PWT and PWL were higher in the MAN group than the SMA group on days 6 and 7, and higher on days 10, 12 and 14 postoperatively (P<0.05 or P<0.01), while the same indices were significantly higher in the MOB group than MAN group on days 1-4 (P<0.05 or P<0.01). The expression of NOS was lower in the MAN and MOB groups than SMA group on day 12 postoperatively (P<0.01).@*CONCLUSIONS@#Both manipulation and mobilization produced better results than sham interference in relieving pain by reducing neuroinflammation possibly. At the early period, compared with manipulation, mobilization presented less sensitive response to pain until later visit. SM may inhibit the overexpression of NOS, thereby alleviating severe radiculopathy.

Effects of biomechanical parameters of spinal manipulation: A critical literature review / 中西医结合学报

Spinal manipulation is a manual treatment technique that delivers a thrust, using specific biomechanical parameters to exert its therapeutic effects. These parameters have been shown to have a unique dose-response relationship with the physiological responses of the therapy. So far, however, there has not been a unified approach to standardize these biomechanical characteristics. In fact, it is still undetermined how they affect the observed clinical outcomes of spinal manipulation. This study, therefore, reviewed the current body of literature to explore these dosage parameters and evaluate their significance, with respect to physiological and clinical outcomes. From the experimental studies reviewed herein, it is evident that the modulation of manipulation's biomechanical parameters elicits transient physiological responses, including changes in neuronal activity, electromyographic responses, spinal stiffness, muscle spindle responses, paraspinal muscle activity, vertebral displacement, and segmental and intersegmental acceleration responses. However, to date, there have been few clinical trials that tested the therapeutic relevance of these changes. In addition, there were some inherent limitations in both human and animal models due to the use of mechanical devices to apply the thrust. Future studies evaluating the effects of varying biomechanical parameters of spinal manipulation should include clinicians to deliver the therapy in order to explore the true clinical significance of the dose-response relationship.

Traumatic Atlantoaxial Rotatory Subluxation in Adult: Case Report

Traumatic atlantoaxial rotatory subluxation (AARS) is generally found in pediatric patients, rarely found in adults, being a life-threatening condition especially when early diagnosis is not possible, which can lead to severe late neurological deficits.We describe a 38-year-old patient, victim of physical aggression caused by strangulation attempt who developed AARS, an uncommontraumatic cause. During the hospital care, the early diagnosis allowed us to institute a conservative treatment, which made the case uncommon, since most of the time surgical treatment is imperative. With the patient awake and under analgesia, a closed reduction was performed that promoted immediate pain relief, followed by a prescription of wearing a Philadelphia-type collar for 8 weeks. During the follow-up, cervical spine radiographies demonstrated no subluxation after removing the cervical collar. The patient was asymptomatic after 6months of treatment. This case supports the importance of nonoperative management of AARS in selected cases.

Efeito da mobilização neural no tratamento da dor em indivíduos com cervicobraquialgia: uma revisão sistemática / Effect of neural mobilization on the treatment of pain in individuals with cervicobrachialgia: a systematic review

: A cervicobraquialgia (CB) é caracterizada por uma dor com origem em diferentes níveis estruturais da coluna cervical baixa (C3- C7), com irradiação bilateral ou unilateral para o membro superior. Considerando as causas e consequências advindas da CB, novas modalidades de tratamento têm sido propostas na tentativa de promover intervenções efetivas. Entre os procedimentos fisioterapêuticos encontram-se as técnicas de terapia manual como liberação miofascial, quiropraxia, mobilização articular, estabilização segmentar e a mobilização neural (MN) que procura restabelecer a função do tecido neural, sua condução elétrica, elasticidade, movimento e fluxo axoplasmático. Sendo assim, o objetivo do estudo foi avaliar sistematicamente as evidências sobre o efeito da MN no tratamento da dor em indivíduos com CB. A busca bibliográfica foi realizada no período entre Novembro de 2018 a Junho de 2019, sem limite de ano de publicação, nas bases de dados: PEDro, PubMed, Biblioteca Virtual em Saúde (Lilacs, Scielo e Medline) e Cochrane Library. A análise foi restrita aos ensaios clínicos randomizados. Para a análise etodológica dos artigos aptos a inclusão, foi utilizada a escala PEDro. Foi encontrado um total de 38 artigos. Após remoção de duplicatas, 14 artigos foram elegidos por resumo, 8 artigos foram recuperados para leitura completa e analisados quanto a sua adequação, dos quais 3 foram excluídos por não cumprirem os critérios de elegibilidade, ao fim 5 artigos foram incluídos na revisão. Houve redução significativa da dor, em pacientes tratados com MN. Considerando os resultados obtidos nesta revisão, foi possível concluir que a MN demonstra ser eficaz na redução da dor presente na CB. Embora os estudos mostrem que os resultados da MN como tratamento da CB são significativamente inferiores ao efeito do Ibuprofeno, deve-se ter em consideração as consequências a longo prazo para a saúde sobre a utilização de anti- inflamatórios orais.(AU)

Cervicobrachialgia (CB) is characterized by pain originating from different structural levels of the lower cervical spine (C3-C7), w ith bilateral or unilateral irradiation to the upper limb. Considering the causes and consequences of CB, new treatment modalities have been proposed in an attempt to promote effective interventions. Among the physical therapy procedures are manual therapy techniques such as myofascial release, chiropractic, joint mobilization, segmental stabilization and neural mobilization (NM) that seeks to restore the function of neural tissue, its electrical conduction, elasticity, movement and ax oplasmic flow . Thus, the objective of the study w as to evaluate systematically evaluate the evidence on the effect of NM on pain management in individuals w ith CB. The bibliographic search w as performed from November 2018 to June 2019, w ithout limit of year of publication, in the databases: PEDro, PubMed, Virtual Health Library (Lilacs, Scielo and Medline) and Cochrane Library. The analysis w as restricted to randomized controlled trials. For the methodological analysis of the articles eligible for inc lusion, the PEDro scale w as used. A total of 38 articles w ere found. After removal of duplicates, 14 articles w ere elected by abstract, 8 articles w ere retrieved for full reading and analyzed for suitability, of w hich 3 w ere excluded for not meeting eligibility c riteria, at the end 5 articles w ere included in the review . There was a significant pain reduction in patients treated w ith NM. Considering the results obtained in this review , it w as concluded that NM demonstrates to be effective in reducing pain present in CB. Although studies show that the results of NM as a treatment for CB are significantly low er than the effect of ibuprofen, consideration should be given to the long-term health consequences about the utilization of oral anti-inflammatory drugs.(AU)

Clinical effect of lever positioning manipulation for lumbar disc herniation and its influence on Cobb angle / 中国骨伤

OBJECTIVE@#To observe the clinical effect of lever positioning manipulation for the treatment of lumbar disc herniation and its effect on Cobb angle.@*METHODS@#From December 2017 to November 2018, 67 patients with lumbar disc herniation were included in the study. The patients were randomly divided into treatment group and control group by digital table method. There were 34 cases in the treatment group, including 20 males and 14 females, with an average age of (36.09±8.26) years old and a course of (13.79±15.50) months. Treatment group was treated with lever positioning manipulation. There were 33 cases in the control group, including 18 males and 15 females, with an average age of(36.48±7.81) years old and a course of (12.82±15.68) months. Control group was treated with lumbar slanting manipulation. Two groups were treated 3 times a week, once every other day, 6 times for a course of treatment, after 2 courses of treatment, the changes of Cobb angle before and after treatment were compared between two groups by imaging. The symptoms and signs were scored with reference to clinical evaluation standard;overall efficacy was evaluated with reference to "Diagnostic Efficacy Criteria of Traditional Chinese Medicine Syndrome" issued by the State Administration of Traditional Chinese Medicine for lumbar disc herniation.@*RESULTS@#One patient in each group dropped out. The symptom and sign scores of treatment group and control group before treatment were 18.56± 4.81, 18.61±3.72, while after treatment were 9.41±5.19, 13.55±3.68;treatment group was significantly lower than control group after treatment (@*CONCLUSION@#Both the lever positioning manipulation and the lumbar slanting manipulation methods are effective for the treatment of lumbar disc herniation, but clinical effect of lever positioning method on lumbar disc herniation is more significant, and the effect on Cobb angle is more obvious. It is worthy of promotion.

Four-rod Technique Stabilization after Pedicle Subtraction Osteotomy (PSO) for the Treatment of Thoracolumbar Hyperkyphosis Secondary to Pott Disease: A Two-Year Follow-Up Case Report

Pedicle subtraction osteotomy (PSO) is a powerful tool for themanagement of sagittal misalignment. However, this procedure has a high rate of implant failure, particularly rod breakages. The four-rod technique diminishes this complication in the lumbar spine. The aim of the present study is to provide a case report regarding PSO and fourrod technique stabilization in the treatment of short-angle hyperkyphosis in the thoracolumbar (TL) junction. The authors describe the case of a patient with TL hyperkyphosis secondary to spinal tuberculosis treated with L1 PSO and fixation with a four-rod technique. There were no major surgical complications. The self-reported quality of life questionnaires (the Short-Form Health Survey 36 [SF-36] and the Oswestry disability index) and radiological parameters were assessed preoperatively, as well as 6, 12 and 24 months after surgery, and they showed considerable and sustained improvements in pain control and quality of life. No hardware failure was observed at the two-year follow-up.

Kinematic parameters and related influencing factors of sitting lumbar spine manipulation with motion capture / 中国骨伤

OBJECTIVE@#To explore the influence of individual characteristics of patients on the kinematics parameters of sitting lumbar spine manipulation.@*METHODS@#From January 2016 to December 2016, 30 patients with degenerative lumbar spondylolisthesis were treatede, including 18 males and 12 females, aged from 45 to 61(52.33±2.34) years old, with a course of 2 to 72(29.13±3.23) months. Motion capture technique was used to measure the kinematics parameters of the same manipulator in sitting lumbar spine manipulation for 30 patients, including rotation time, maximum speed and maximum acceleration. The parameters of the left and right hands of the operator were different. The effects of individual characteristics on the kinematics parameters of sitting lumbar spine manipulation were analyzed.@*RESULTS@#The kinematic and mechanical parameters of manipulation were as follows:spin time, maximum speed, maximum acceleration, the manipulation done by right or left hand showed the similar parameters(>0.05). According to multivariate linear regression, there was a significant correlation between the age of the patient and the rotation time of the operator(<0.01); the height of patient had a significant correlation with the maximum speed and maximum acceleration of the operator(<0.01).@*CONCLUSIONS@#There is no difference between the manipulation of left and right hand in clinical application. Age and height are important influencing factors of sitting lumbar rotation manipulation.

A Case of Posterior Inferior Cerebellar Artery Infarction after Cervical Chiropractic Manipulation / 대한신경손상학회지

We describe the case of a patient who had infarction of the posterior inferior cerebellar artery (PICA) after a chiropractic cervical manipulation. A 39-year-old man visited the emergency room with signs of cerebellar dysfunction, presenting with a 6-hour history of vertigo and imbalance. Two weeks ago, he was treated by a chiropractor for intermittent neck pain. At the time of admission, brain computed tomography, magnetic resonance imaging, and angiography revealed an acute infarction in the left PICA territory and occlusion of the extracranial vertebral artery (VA; V1/2 junction) as a result of the dissection of the VA. Angiography revealed complete occlusion of the left PICA and arterial dissection was shown in the extracranial portion of the VA. He was treated with antiplatelet therapy. Three weeks later, he was discharged without any sequelae. The possibility of VA dissection should be considered at least once in patients presenting with cerebellar dysfunctions with a recent history of chiropractic cervical manipulation.

Tonic Investigation Concept of Cervico-vestibular Muscle Afferents

Abstract Introduction Interdisciplinary research has contributed greatly to an improved understanding of the vestibular system. To date, however, very little research has focused on the vestibular system's somatosensory afferents. To ensure the diagnostic quality of vestibular somatosensory afferent data, especially the extra cranial afferents, stimulation of the vestibular balance system has to be precluded. Objective Sophisticated movements require intra- and extra cranial vestibular receptors. The study's objective is to evaluate an investigation concept for cervico-vestibular afferents with respect to clinical feasibility. Methods A dedicated chair was constructed, permitting three-dimensional trunk excursions, during which the volunteer's head remains fixed. Whether or not a cervicotonic provocation nystagmus (c-PN) can be induced with static trunk excursion is to be evaluated and if this can be influenced by cervical monophasic transcutaneous electrical nerve stimulation (c-TENS) with a randomized test group. 3D-video-oculography (VOG) was used to record any change in cervico-ocular examination parameters. The occurring nystagmuses were evaluated visually due to the small caliber of nystagmus amplitudes in healthy volunteers. Results The results demonstrate: no influence of placebo-controlled c-TENS on the spontaneous nystagmus; a significant increase of the vertical nystagmus on the 3Dtrunk- excursion chair in static trunk flexion with cervical provocation in all young healthy volunteers (n = 49); and a significant difference between vertical and horizontal nystagmuses during static trunk excursion after placebo-controlled c-TENS, except for the horizontal nystagmus during trunk torsion. Conclusion We hope this cervicotonic investigation concept on the 3D trunk-excursion chair will contribute to new diagnostic and therapeutic perspectives on cervical pathologies in vestibular head-to-trunk alignment.

Effects of cervical mobilization and exercise on pain, movement and function in subjects with temporomandibular disorders: a single group pre-post test

ABSTRACT Objective To investigate the effect of a rehabilitation program based on cervical mobilization and exercise on clinical signs and mandibular function in subjects with temporomandibular disorder (TMD). Material and Methods: Single-group pre-post test, with baseline comparison. Subjects Twelve women (22.08±2.23 years) with myofascial pain and mixed TMD according to the Research Diagnostic Criteria for Temporomandibular Disorders. Outcome measures Subjects were evaluated three times: twice before (baseline phase) and once after intervention. Self-reported pain, jaw function [according to the Mandibular Functional Impairment Questionnaire (MFIQ)], pain-free maximum mouth opening (MMO), and pressure pain thresholds (PPTs) of both masseter and temporalis muscles were obtained. Baseline and post-intervention differences were investigated, and effect size was estimated through Cohen’s d coefficient. Results Jaw function improved 7 points on the scale after the intervention (P=0.019), and self-reported pain was significantly reduced (P=0.009). Pain-free MMO varied from 32.3±8.8 mm to 38±8.8 mm and showed significant improvement (P=0.017) with moderate effect size when compared to the baseline phase. PPT also increased with moderate effect size, and subjects had the baseline values changed from 1.23±0.2 kg/cm2 to 1.4±0.2 kg/cm2 in the left masseter (P=0.03), from 1.31±0.28 kg/cm2 to 1.51±0.2 kg/cm2 in the right masseter (P>0.05), from 1.32±0.2 kg/cm2 to 1.46±0.2 kg/cm2 in the left temporalis (P=0.047), and from 1.4±0.2 kg/cm2 to 1.67±0.3 kg/cm2 in the right temporalis (P=0.06). Conclusions The protocol caused significant changes in pain-free MMO, self-reported pain, and functionality of the stomatognathic system in subjects with myofascial TMD, regardless of joint involvement. Even though these differences are statistically significant, their clinical relevance is still questionable.

Case-control study on three spinal rotation manipulations for the treatment of lumbar disc herniation / 中国骨伤

<p><b>OBJECTIVE</b>To evaluate the efficacy and safety of three different spinal rotation manipulations for the treatment of lumbar disc herniation.</p><p><b>METHODS</b>From September 2011 to April 2013,180 patients diagnosed as lumbar disc herniation were randomly divided into seat fixed rotation group (A), lateral position rotation group (B) and supine position rotation group (C) by using a digital table. Finally 10 patients were excluded and dropped, 170 patients were included in the study. There were 57 patients in group A, 57 patients in group B and 56 patients in group C. Baseline demographic characteristics of patients, clinical findings and indexes of health status had no statistically differences among three groups (P > 0.05). The manipulation was performed every other day, and the treatment duration for all patients was 3 weeks. Body pain (BP), Physical function (PF) in SF-36, Oswestry Disability Index (ODI) and adverse reactions were observed statistically 6 weeks, 3 months, 6 months, one year and two years after finishing treatment.</p><p><b>RESULTS</b>BP, PF scores in 3 groups were significantly improved and ODI scores were significantly lower than those before treatment and the differences were statistically significant (P < 0.05); However, there was no significant difference among three groups in the BP, PF and ODI scores (P > 0.05). There were no obvious and serious adverse reactions among these groups.</p><p><b>CONCLUSION</b>Based on the theory of dislocation of bone joints in TCM, three kinds of spinal rotation manipulations can be used safely for the treatment of lumbar disc herniation, and the efficacy was similar.</p>

Immediate effects of upper thoracic manipulation on the skin surface temperature of the vertebral region in healthy women / Efeitos imediatos da manipulação torácica alta sobre a temperatura superficial cutânea da região vertebral em mulheres saudáveis / Los efectos inmediatos de la alta manipulación torácica de la temperatura superficial de la piel en la región vertebral en mujeres sanas

Manipulation of the spinal column is a manual therapeutic resource characterized by passive thrust of a given joint at a high velocity and low amplitude within the limits of anatomic integrity. The objective of the present study was to assess the immediate effects of upper thoracic manipulation on skin temperature in the vertebral region in healthy women. Thus, a randomized controlled blind trial was realized in the university community. Twenty-six healthy women were randomly allocated into an experimental group (n=13) and a placebo group (n=13). A single session of upper thoracic spine manipulation (segment T3) was performed. Infrared thermography was used to determine changes in skin temperature in the vertebral region. Images were taken prior to, immediately after and both five and 10 minutes after manipulation. Two-way repeated measures analysis of variance with post hoc Bonferroni test was used for inter and intragroup comparisons. The level of significance was set to 5%. No significant differences were found between the different evaluation times in either group (p>0.05). In the intergroup analysis, no statistically significant differences were found in any of the comparisons (p>0.05). Based on the method employed, thoracic spine manipulation of the T3 vertebral segment does not promote changes in skin surface temperature in the region manipulated in asymptomatic individuals.

A manipulação da coluna vertebral é um recurso da terapia manual caracterizado por um impulso passivo de alta velocidade e baixa amplitude dentro dos limites de integridade anatômica de uma articulação (thrust). O objetivo do presente estudo foi avaliar os efeitos imediatos da manipulação torácica alta sobre a temperatura superficial cutânea da região vertebral em mulheres saudáveis. Para tal, foi realizado um estudo clínico randomizado cego na comunidade universitária. Vinte e seis voluntárias saudáveis foram alocadas de forma randomizada em um grupo experimental (n=13) e um grupo placebo (n=13). Uma sessão de manipulação torácica alta (segmento T3) foi realizada. Foi empregada a termografia infravermelha para determinar alterações na temperatura cutânea na região vertebral. Imagens foram capturadas antes, imediatamente após, cinco e dez minutos após a manipulação. Foi usada análise de variância com medidas repetidas (dois critérios) seguida do teste de Bonferroni para as comparações inter e intragrupos. Adotou-se um nível de significância de 5%. Não foi encontrada diferença significativa nas diferentes avaliações ao longo do tempo (p>0,05). Na análise intergrupos, não foi constatada diferença significativa nas comparações realizadas (p>0,05). Com base na metodologia empregada, a manipulação torácica do segmento vertebral T3 não promoveu alterações na temperatura superficial cutânea na região manipulada.

La manipulación de la espina dorsal es un recurso de terapia manual que se caracteriza por un impulso pasivo de alta velocidad y baja amplitud de los límites de integridad anatómica de una articulación (thrust). Esta investigación tuvo por objetivo evaluar los efectos inmediatos de la alta manipulación torácica de la temperatura superficial de la piel en la región vertebral en mujeres sanas. Para eso, se ha realizado un estudio clínico aleatorizado ciego en la comunidad universitaria. Veintiséis voluntarias han sido puestas de forma aleatorizada en un grupo experimental (n=13) y un grupo placebo (n=13). Ha sido realizada una sesión de manipulación torácica alta (segmento T3). Se ha empleado el término infrarrojo para determinar alteraciones en la temperatura de la piel en la región vertebral. Se han capturado imágenes antes, inmediatamente después, cinco y diez minutos tras la manipulación. Se ha hecho un análisis de los cambios con medidas repetidas (dos criterios) seguido de la prueba de Bonferroni para las comparaciones inter e intragrupal. Se ha adoptado un nivel de significancia de 5%. No ha sido encontrado diferencias significativas en las diferentes evaluaciones al largo del tiempo (p>0,05). En el análisis intergrupal, no ha sido constatado diferencias significativas en las comparaciones realizadas (p>0,05). Basándose en la metodología empleada, la manipulación torácica del segmento vertebral T3 no cambió la temperatura superficial de la piel en la región estudiada.

Immediate electromyographic changes of the upper limb muscles following cervical manipulation in a patient with essential tremor: a case report / Alterações eletromiográficas imediatas dos músculos dos membros superiores após manipulação cervical em uma paciente com tremor essencial: estudo de caso

Introduction and Objective: The purpose of this case report is to evaluate upper limb muscle electric behavior by surface electromyography before and after cervical manipulation in a patient with essential tremor. Methods: In 2009, essential tremor was diagnosed by a neurologist in a 25-year-old woman. Previous treatment included Paroxetine for a number of months, without alteration of her symptoms. The patient was assessed by surface electromyography of the upper limb muscles (flexor and extensor of the wrist, long heads of biceps and triceps) before and after being subjected to high-velocity, low-amplitude spinal manipulation to her mid cervical spine (C3-C4 level, 1 manipulation/side). Results: There was an increase of the median frequency rate and a decrease of the electrical activity of these muscles. Conclusion: This case study showed the cervical manipulation technique acutely modifying the electromyographic activity, increasing the median frequency, and decreasing the muscle recruitment of the upper limb. It suggests improved motor control during the tasks.

Introdução e Objetivo: O objetivo neste estudo de caso foi avaliar o comportamento elétrico dos músculos do membro superior, por eletromiografia, antes e após manipulação cervical em paciente com tremor essencial. Métodos: Uma mulher (25 anos) apresentou-se com tremor essencial, diagnosticado em 2009 por neurologista. Foi empregado tratamento prévio com Paroxetina por meses, sem diminuição dos sintomas. A paciente foi avaliada por eletromiografia dos músculos dos membros superiores (flexores e extensores do punho, cabeça longa do bíceps e do tríceps) antes e após manipulação de alta velocidade e baixa amplitude na cervical média (nível C3-C4, 1 manipulação para cada lado). Resultados: Observou-se aumento na frequência mediana e diminuição na atividade elétrica dos músculos avaliados. Conclusão: A técnica de manipulação cervical modificou de forma imediata a atividade eletromiográfica, aumentando a frequência mediana e diminuindo o recrutamento dos músculos do membro superior para a paciente estudada, sugerindo melhor controle motor durante a atividade proposta.

Effect of spinal manipulation on brain functional activity in patients with lumbar disc herniation / 浙江大学学报·医学版

<p><b>OBJECTIVE</b>To investigate the effects of spinal manipulation (SM) on brain functional activity in patients with lumbar disc herniation (LDH).</p><p><b>METHODS</b>Eleven patients with LDH were recruited in the study. All patients received 6 times of lumbar SM treatment and then clinical efficacy was evaluated. All patients received brain functional magnetic resonance imaging (fMRI) scans before and after SM treatment.</p><p><b>RESULTS</b>Three subjects dropped out and 8 subjects completed the study, among whom 4 cases were effective and 4 ineffective after SM treatment. The required pressure value producing the same level (VAS 50) pain was (7.43 ± 1.47) kg and (10.53 ± 0.55) kg before and after SM treatment in effective patients(P<0.05); however, there was no significant difference in ineffective patients (P>0.05). Compared to pre-treatment level, the brain functional activity in effective patients was mainly inhibited, the inhibited areas were located in the right side of prefrontal cortex and cerebellum; while the brain functional activity was generally enhanced in ineffective patients.</p><p><b>CONCLUSION</b>SM can affect the brain functional activity of patients with LDH, the inhibited areas is mainly located in prefrontal cortex and cerebellum when SM treatment is effective.</p>

Effectiveness of manipulative reduction combined with minimally invasive surgery in the treatment of osteoporotic vertebral compression fracture: a meta-analysis / 中国骨伤

<p><b>OBJECTIVE</b>To evaluate the clinical efficacy of manipulative reduction combined with percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) in treating osteoporotic vertebral compression fracture (OVCF) using meta-analysis method, in order to provide a reference for clinical treatment.</p><p><b>METHODS</b>A systematic computer-based search (from January 1987 to April 2014) from CNKI, Wanfang database, Web of Science and PubMed were performed for the collection of controlled clinical researches on manipulative reduction combined with PVP or PKP in treating OVCF. The quality of selected researches was evaluated. Meta-analysis was adopted to evaluate visual analog scale, Cobb angle, anterior height ratio of the injured vertebra.</p><p><b>RESULTS</b>A total of 7 researches of 410 patients were included in the present analysis, there were 5 RCTs and 2 non-RCTs and all come from China. Manipulative reduction combined with PVP could got better improvement in Cobb angle (WMD=-7.35; 95%CI: -12.15, -2.54) and anterior height ratio of the injured vertebra (P<0.01) than simple PVP, but no significant difference was found in improvement of visual analog scale (WMD=-0.01; 95%CI: -0.45, 0.42). There were no significant differences in the improvement of visual analog scale, Cobb angle, anterior height ratio of the injured vertebra between manipulative reduction combined with PKP and simple PKP (P>0.05).</p><p><b>CONCLUSION</b>Compared with simple PVP, manipulative reduction combined with PVP may result in more clinical efficacy on the improvement of Cobb angle and anterior ratio of the injured vertebra. And compared with simple PKP, manipulative reduction combined with PKP has no obvious advantages on the improvement of visual analog scale, Cobb angle, anterior height ratio of the injured vertebra. However, the number and quality of the literatures, may resulted in the effect of mistrust, so more large sample and high-quality RCTs are needed in future.</p>

Case-control study on bone-setting manipulation for the treatment of isolated systolic hypertension combined with cervical spondylosis / 中国骨伤

<p><b>OBJECTIVE</b>To investigate clinical effect and safety of bone-setting manipulation in treating isolated systolic hypertension combined with cervical spondylosis.</p><p><b>METHODS</b>From January 2012 to January 2015, 320 patients suffered from isolated systolic hypertension combined with cervical spondylosis were randomly divided into treatment group and control group. In treatment group, there were 160 patients including 84 males and 76 females with an average age of (39.82 ± 10.33) years old, average blood pressure was (149.61 ± 10.75)/(81.01± 8.25) mmHg, NPQ score was 24.61 ± 8.14; treated with flexion top spin and lock bone-setting manipulation of cervical spine, once every two days for 20 days. While in control group, there were 160 patients including 90 males and 70 females with an average age of(41.37 ± 9.42) years old, average blood pressure was (151.48 ± 11.32)/ (79.65 ± 9.32) mmHg, NPQ score was 25.78 ± 9.53; treated with manipulation of reposition cervical spine by rotation, once every two days for 20 days. Blood pressure and NPQ score were tested and compared for evaluating clinical effects.</p><p><b>RESULTS</b>Before and after a period treatment, systolic pressure in treatment group was (149.61 ± 10.75) mmHg and (129.67 ± 12.26) mmHg; (151.48 ± 11.32) mmHg and (132.02 ± 11.73) mmHg in control group. After treatment, systolic pressure in both two groups was obviously decreased, and treatment group was better than control group. Before and after a period treatment, diastolic pressure in treatment group was (80.01 ± 8.25) mmHg and (78.15 ± 10.34) mmHg, (79.65 ± 9.32) mmHg and (76.89 ± 9.79) mmHg in control group, and there was no significant difference between two groups. NPQ score in treatment group was 24.61 ± 8.14 before treatment, 12.46 ± 7.94 after treatment, while in control group was 25.78 ± 9.53, 14.17 ± 8.86; NPQ score of the two groups after treatment was better than before treatment, while there was no obviously significance between two groups after treatment. The whole clinical effect in treatment group was better than control group.</p><p><b>CONCLUSION</b>Bone-setting manipulation for isolated systolic hypertension combined with cervical spondylosis at early stage could receive good clinical result, and flexion top spin and lock bone-setting manipulation of cervical spine was better and safety than manipulation of reposition cervical spine by rotation.</p>